Searchable abstracts of presentations at key conferences in endocrinology

ea0081oc9.5 | Oral Communications 9: Environmental Endocrinology | ECE2022

Decoding the role of environmental cadmium exposure in thyroid disorders

Buha Aleksandra , Javorac Dragana , Baralic Katarina , Mandic-Rajcevic Stefan , Maric Djurdjica , Antonijevic-Miljakovic Evica , Djukic-Cosis Danijela , Zarkovic Milos , Antonijevic Biljana , Bulat Zorica

As a ubiquitously present metal, cadmium (Cd) represents a matter of great concern, especially considering its potential thyroid disrupting capacity. The study evaluated the connection between this environmentally relevant metal exposure and thyroid hormone levels. The DecodExpo study enrolled 425 participants (207 males and 218 females) with various disorders (236 participants) and healthy controls (189 participants). Collected blood samples were digested, and Cd levels were ...

ea0073aep404 | Environmental Endocrinology | ECE2021

Cadmium levels in human breast tissue and estradiol serum levels: Dose-response data analyses

Buha Aleksandra , Andjelkovic Milena , Javorac Dragana , Katarina Baralić , Kacavenda Elena , Antonijevic Evica , Rajcevic Stefan Mandic , Granic Miroslav , Djukic-Cosic Danijela , Bulat Zorica

Cadmium (Cd) is a ubiquitously present toxic metal with an established ability to induce endocrine disruption, in literature often referred to as metalloestrogen. Some of the major uncertainties connected with endocrine disrupting chemicals (EDCs) in general, are low-dose exposure and the presence of nonmonotonic dose-response curves. This study aims to elucidate the presence of a dose-response relationship between the measured Cd levels in the tissue (internal dose) and estro...